Due to its convenient position at the southern tip of the city of Milan, the shrine of "Madonna of Relief" is easy to reach by all means of public transportation, and is not far from the major highways, toll roads, and airports in the area.

The main way to reach the shrine are :

• Buses from Milan (line 222 of ATM, the pubblic transportation company of Milan - ATM Site)
• State Route "Val Tidone" , with th exit on Opera
• The "Tangenziale Ovest" toll road, which runs around Milan , with an exit on "Val Tidone"
• The railway line from Milan, stopping in Locate Triulzi train station, which is only 5 kilometers from the shrine
• The Linate Airport in Milan, about 15 kilometers from Opera
• The Malpensa Airport in Milan, about 60 kilometers from Opera

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